World Health Organization
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Guidelines for the diagnosis and management of Cystic Fibrosis

CONTENTS
GENETICS PATHOGENESIS Respiratory
System Infection Pancreas Intestines Liver Skin Reproductive System CLINICAL
FEATURES Presenting Features At birth In the first year In the pre-school age
child In the school age child In adolescence and adult life DIAGNOSIS The Sweat
Test Genetic Testing Neonatal Screening Tests for Pancreatic Insufficiency
MANAGEMENT The Newly-Diagnosed
Patient Surveillance Routine Management Treatment of Pulmonary
Manifestations Physiotherapy Exercise Treatment of respiratory infection Staphylococcus
aureus Haemophilus influenzae Pseudomonas aeruginosa Aerosol antibiotics Burkholderia
cepacia Aspergillus Other Respiratory Therapy Gene Therapy Pulmonary Function
Tests Treatment of Pancreatic Insufficiency Nutritional Management Treatment of Meconium
Ileus Treatment of Distal Intestinal Obstruction Syndrome (DIOS) Management of Late and Less
Common Complications FURTHER READING ACKNOWLEDGEMENTS ANNEX
Physiotherapy in the Treatment of Cystic Fibrosis
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5 for 5 Campaign
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